PromethION 24
High-throughput and flexible sequencing at scale
PromethION 24 combines power, flexibility, and scalability to meet the demands of modern high-throughput sequencing.
Advantages
24 independent and controllable flow cells
Real-time DNA and RNA sequencing with integrated basecalling
Massive data output (terabases)
GPU technology and advanced algorithms for fast processing
Modular format designed for demanding research environments
The PromethION 24 is a high-throughput nanopore sequencer designed to deliver maximum flexibility for research laboratories and sequencing facilities. It integrates 24 independent flow cells, each of which can be used separately or simultaneously for true on-demand sequencing.
With powerful built-in compute and GPU acceleration, the PromethION 24 provides large-scale sequencing with real-time analysis. Its modular architecture, including a sequencing unit and a data acquisition unit, ensures easy integration into intensive research workflows.
Capable of generating multiple terabases of data, the PromethION 24 is a reference solution for large-scale genomics, transcriptomics, and complex research applications.
| Component | Specification |
|---|---|
| Size and weight | PromethION 24 Sequencing Unit: H 190 x W 590 x D 430 mm, 23 kg PromethION 48 Sequencing Unit: H 190 x W 590 x D 430 mm, 30 kg PromethION A-Series Data Acquisition Unit: H 470 x W 178 x D 440 mm, 26 kg |
| Data Acquisition Unit specification | 60 TB SSD Storage, 512 GB RAM, 4 x NVIDIA Ampere GPU cards for basecalling acceleration |
| Pre-loaded software | Linux (Ubuntu) OS, PromethION OS (MinKNOW inside), Dorado software |
| Environmental conditions | Designed to sequence at room temperature (+18°C to +22°C) Users should allow 30 cm clearance to the rear and sides of the device. CAUTION: Rear of instrument heats up during operation. |
| Space required | Install the Sequencing Unit and Data Acquisition Unit on a bench. Allow 30 cm clearance to the rear and sides of the device. The PromethION 24 Combined needs to be installed with the Sequencing and Data Acquisition units next to each other. The bench space required for a PromethION installation is 167 cm x 75 cm |
Large-scale human genomics
Comprehensive transcriptomics (direct RNA and cDNA)
Cancer and infectious disease research
Population studies and plant/animal genetics
Metagenomic and microbiological analyses