Physico-chemical testing on pharmaceutical products (tablets, suppositories, capsules…) is a major stage before a batch release. As a consequence, it is crutial to have an equipment which meet your need : in compliance with pharmaceutical norms (EP or USP), robust and reliable. Our solutions are leader in Europe, and our supplier is among the main pharmaceutical companies suppliers. Dissolution tests : In addition to compliance and reliability criteria, we also offer innovative solutions to facilitate analysis considered as difficult (such as dissolution of suppositories within a continuous flow bath (USP4).
Often associated to length and diameter measurements, hardness test consists in applying pressure on the tablet until its breaking point.There are two methods: at constant speed or at constant force; but even if these two methods are described in materia medica, their results are different and not related !That's why we offer you a range of instrument adapted to work with both constant force and constant speed.One of the main difficulties of this test concerns the tablet shape : an oblong (oval) tablet is often hard to maintain lengthwise when a pressure is exerted. The oblong shape makes it slide. For this reason one may have to proceed several times before succeeding... On all of the devices we propose, the self-positioning will enable you to realize measurements without problem, whatever your tablet shapes.According to your speeds, we propose semi-automatic or fully automatic manual versions with weight-in included.
Disintegration consists in making go and come a tablet in a basket until the complete disintegration of it. Plain-looking, this test is not always easy to realize, and the materia medica is evolving. With the DT2, we propose you a system totally in compliance with the norms whatever are the tablet sizes, and progressive to adapt your needs. For the simple applications, a manual bath will be perfect, automatic basket exit otpion will be useful for gastro-resistant tablets, and for the tablets of which the excipients make the middle opaque, the automatic detection will enable you to obatin accurate and repeatable results.
To check the active principle level of a tablet is one of the most important tests before the batch release. If a chromatographic analysis (HPLC) is relatively easy to carry out, the major difficulty of the test come from the sample preparation. Thus, we often notice siezable differences between the different operators while the HLPC method is the same. In order to reduce this variability, and to obtain reliable and repeatable results, we propose you semi automated or fully automated solutions to put tablets into solution. This investment guarantees considerable time saving and therfore money saving in accordance with your cadences !! For more details and an offer adapted to your problematic contact us.