Zetasizer Ultra
Malvern panalytical
World’s most advanced light scattering system
The new Zetasizer Ultra is our most advanced system for the measurement of particle and molecular size, particle charge and particle concentration, and represents the most intelligent and flexible instrument in the Zetasizer Advance range.
Advantages
- Multi-Angle Dynamic Light Scattering (MADLS) for absolute confidence in particle and molecular size distribution analysis
- Dynamic Light Scattering (DLS) measures particle and molecule size, from below 1 nm to 10 µm
- Electrophoretic Light Scattering (ELS) measures the zeta potential of particles and molecules, indicating sample stability and/or propensity to aggregate
- Non-Invasive Back Scatter (NIBS) optics for versatile, high sensitivity, particle and molecular size measurements
- Simple, per-peak concentration / titer measurements (Red Label only)
- Disposable capillary sizing cell provides the ultimate in non-destructive, low volume (down to 3 µL) analysis, with an upper size range that extends to 10 μm
- M3-PALS with Constant Current Mode for zeta potential and electrophoretic mobility measurements
- ZS Xplorer software suite for simple and flexible method set-up and data analysis
- Adaptive Correlation for faster, more reproducible sizing measurements with less sample preparation
- Deep Learning empowered data quality system for assessment of any size data quality issues, with clear advice on how to improve results
- Optical filter wheel with fluorescence filter to allow measurement of fluorescent samples without impairing overall system sensitivity. Also includes polarization filters for DDLS measurements
- The optional MPT-3 Autotitrator enables study of the effect of changes in pH
Description
Specification
Applications
Resources
Our flagship model enjoys all the benefits afforded by ZS Xplorer software, in terms of ease of use, analysis speed and data confidence, and also offers two unique measurement capabilities: Multi-Angle Dynamic Light Scattering (MADLS®) and particle concentration*, to offer even greater insight into your samples.
Particle size and molecular size
| Measurement principle | Non-Invasive Back Scatter (NIBS) Dynamic Light Scattering Dynamic Light Scattering (90° and 13°) Multi-Angle Dynamic Light Scattering (MADLS) |
|---|---|
| Measurement angle | 173°, 13°, 90° |
| Measurement range | Diameter: 0.3 nm – 15 μm (2) (9) |
| Minimum sample volume | 3 μL |
| Concentration range | Minimum sample concentration: Blue Label: 0.2 mg/mL 15 kDa Protein Red Label: 0.1 mg/mL 15 kDa Protein MADLS: 0.1 mg/ml 15 kDa Protein MADLS Particle Concentration Enabled? Blue Label: No Red Label: Yes Maximum sample concentration(3): 40% w/v |
Zeta potential
| Measurement principle | Mixed-Mode Measurement phase analysis light scattering (M3-PALS) |
|---|---|
| Size range | 3.8 nm – 100 μm |
| Minimum sample volume | 20 μL (4) |
| Concentration range | Red Label: 1 mg/mL (5) to 40% w/v (6) Blue Label: 10 mg/mL (5) to 40% w/v (6) |
| Sample conductivity range | Maximum: 260 mS/cm |
Static Light Scattering (molecular weight)
| Molecular weight range | 980 Da – 20 MDa |
|---|---|
| Measurement principle | Static Light Scattering with Debye Plot (10) |
| Accuracy | +/- 10% typical |
Particle concentration
| Measurement principle | Blue Label: N/A Red Label: MADLS – Particle Concentration (Mie) |
|---|---|
| Concentration range | Blue Label: N/A Red Label: 1×108 to 1×1012 particles/mL |
| Calibration type | Blue Label: N/A Red Label: Single point system calibration only |
System
| Detector | Avalanche Photodiode |
|---|---|
| Laser safety | He-Ne (633 nm) Blue label: 4 mW Max Red label: 10 mW Max |
| Temperature control range | 0°C to 120°C (7) |
| Dimensions (W, D, H) | 322 mm x 565 mm x 245 mm |
| Weight | 19 kg |
| Power | AC 100-240 V, 50-60 Hz, 4.0 A |
| Power consumption | Max 100 W, Typical 45 W |
| Ambient conditions | +10°C to +35°C, 35 – 80% RH (non-condensing) |
| Interface | USB 2.0 or higher |
- Academia
- Bioscience
- Food and drink
- Nanomaterials
- Paints, inks and coatings
- Pharmaceuticals
