for the Dissolution Testing USP 1,2,5,6 Contact
about the Dissolution Testing USP 1,2,5,6
Defining the level of automation that best fits the product and throughput requirements can help to ensure reproducibility and standardization of your dissolution test. The sequence of individual process steps before (pre-run), during (dissolution run), and after (post-run)
- Manual automation level
- Semi-automatic automation level
- Automatic automation level
When dissolution is performed manually, every process step before, during, and after the test is executed manually by the user. This is the most technician-dependent way of testing.
Semi-automated (Single System)
Semi-automated systems ensure that all sequential steps during the dissolution run are reproducibly executed without requiring user interaction until the post-run activity. A semi-automated single dissolution system will give the user the throughput of one dissolution bath, i.e. test 6 samples.
Semi-automated (Double System)
With a semi-automated double system all sequential steps during the dissolution run are reproducibly executed without requiring user interaction until the post-run activity. Compared to a single system, a double dissolution system will give the user the possibility to increase his throughput by using two dissolution baths, i.e. test 12 samples.
- Manual: technician dependent pre-run, dissolution run and post-run
- Semi-automatic: technician dependent pre-run and post-run. technician independent dissolution run
- Automatic: technician independent pre-run, dissolution run and post-run
- Research and development
- Academic laboratories